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Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation
Oxygen sensing is crucial for adaptation to variable habitats and physiological conditions. Low oxygen tension, or hypoxia, is a common feature of solid tumors, and hypoxic tumors are often more aggressive and resistant to therapy. Here we show that, in cultured mammalian cells, hypoxia suppressed l...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896048/ https://www.ncbi.nlm.nih.gov/pubmed/31717697 http://dx.doi.org/10.3390/cancers11111653 |