The Role of Co-Deleted Genes in Neurofibromatosis Type 1 Microdeletions: An Evolutive Approach

Neurofibromatosis type 1 (NF1) is a cancer predisposition syndrome that results from dominant loss-of-function mutations mainly in the NF1 gene. Large rearrangements are present in 5–10% of affected patients, generally encompass NF1 neighboring genes, and are correlated with a more severe NF1 phenot...

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Detalles Bibliográficos
Autores principales: Brussa Reis, Larissa, Turchetto-Zolet, Andreia Carina, Fonini, Maievi, Ashton-Prolla, Patricia, Rosset, Clévia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896060/
https://www.ncbi.nlm.nih.gov/pubmed/31652930
http://dx.doi.org/10.3390/genes10110839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896060/
https://www.ncbi.nlm.nih.gov/pubmed/31652930
http://dx.doi.org/10.3390/genes10110839

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