PIK3CA Cooperates with KRAS to Promote MYC Activity and Tumorigenesis via the Bromodomain Protein BRD9

Tumor formation is generally linked to the acquisition of two or more driver genes that cause normal cells to progress from proliferation to abnormal expansion and malignancy. In order to understand genetic alterations involved in this process, we compared the transcriptomes of an isogenic set of br...

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Detalles Bibliográficos
Autores principales: Bell, Catherine M., Raffeiner, Philipp, Hart, Jonathan R., Vogt, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896067/
https://www.ncbi.nlm.nih.gov/pubmed/31652979
http://dx.doi.org/10.3390/cancers11111634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896067/
https://www.ncbi.nlm.nih.gov/pubmed/31652979
http://dx.doi.org/10.3390/cancers11111634

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