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PIK3CA Cooperates with KRAS to Promote MYC Activity and Tumorigenesis via the Bromodomain Protein BRD9
Tumor formation is generally linked to the acquisition of two or more driver genes that cause normal cells to progress from proliferation to abnormal expansion and malignancy. In order to understand genetic alterations involved in this process, we compared the transcriptomes of an isogenic set of br...
Autores principales: | Bell, Catherine M., Raffeiner, Philipp, Hart, Jonathan R., Vogt, Peter K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896067/ https://www.ncbi.nlm.nih.gov/pubmed/31652979 http://dx.doi.org/10.3390/cancers11111634 |
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