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CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary

Most high-grade serous ovarian cancers (HGSCs) initiate from the fallopian tube epithelium and then metastasize to the ovary and throughout the abdomen. Genomic analyses suggest that most HGSCs seed the ovary prior to abdominal dissemination. Similarly, animal models support a critical role for the...

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Detalles Bibliográficos
Autores principales: Bai, Shoumei, Zhu, Wanhong, Coffman, Lan, Vlad, Anda, Schwartz, Lauren E., Elishaev, Esther, Drapkin, Ronny, Buckanovich, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896092/
https://www.ncbi.nlm.nih.gov/pubmed/31684072
http://dx.doi.org/10.3390/cancers11111710