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HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway

Gastric cancer (GC) remains a health issue due to the low efficiency of therapies, such as cisplatin. This unsatisfactory situation highlights the necessity of finding factors impacting GC sensibility to therapies. We analyzed the cisplatin pangenomic response in cancer cells and found HDAC4 as a ma...

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Detalles Bibliográficos
Autores principales: Spaety, Marie-Elodie, Gries, Alexandre, Badie, Amandine, Venkatasamy, Aina, Romain, Benoit, Orvain, Christophe, Yanagihara, Kazuyoshi, Okamoto, Koji, Jung, Alain C., Mellitzer, Georg, Pfeffer, Sébastien, Gaiddon, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896094/
https://www.ncbi.nlm.nih.gov/pubmed/31703394
http://dx.doi.org/10.3390/cancers11111747