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Targeting STAT3 in Cancer with Nucleotide Therapeutics

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in promoting the proliferation and survival of tumor cells. As a ubiquitously-expressed transcription factor, STAT3 has commonly been considered an “undruggable” target for therapy; thus, much research has focused on ta...

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Detalles Bibliográficos
Autores principales: K. Lau, Yue-Ting, Ramaiyer, Malini, E. Johnson, Daniel, R. Grandis, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896109/
https://www.ncbi.nlm.nih.gov/pubmed/31671769
http://dx.doi.org/10.3390/cancers11111681