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DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression

Cell contact inhibition (CCI) is deregulated in cancer. Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. We found that dual-specificity phosphatase 10 (DUSP10) is involved in CRC. DUSP10 overexpression increased the growth of CRC cell lines and mouse xenografts, while t...

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Detalles Bibliográficos
Autores principales: Jiménez-Martínez, Marta, Ostalé, Cristina M., van der Burg, Lennart R., Galán-Martínez, Javier, Hardwick, James C. H., López-Pérez, Ricardo, Hawinkels, Lukas J. A. C., Stamatakis, Konstantinos, Fresno, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896144/
https://www.ncbi.nlm.nih.gov/pubmed/31717606
http://dx.doi.org/10.3390/cancers11111767