Cargando…

DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression

Cell contact inhibition (CCI) is deregulated in cancer. Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. We found that dual-specificity phosphatase 10 (DUSP10) is involved in CRC. DUSP10 overexpression increased the growth of CRC cell lines and mouse xenografts, while t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiménez-Martínez, Marta, Ostalé, Cristina M., van der Burg, Lennart R., Galán-Martínez, Javier, Hardwick, James C. H., López-Pérez, Ricardo, Hawinkels, Lukas J. A. C., Stamatakis, Konstantinos, Fresno, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896144/ https://www.ncbi.nlm.nih.gov/pubmed/31717606 http://dx.doi.org/10.3390/cancers11111767

Ejemplares similares

The Dual-Specificity Phosphatase 10 (DUSP10): Its Role in Cancer, Inflammation, and Immunity
por: Jiménez-Martínez, Marta, et al.
Publicado: (2019)

Isoform‐specific effects of transcription factor TCFL5 on the pluripotency‐related genes SOX2 and KLF4 in colorectal cancer development
por: Galán‐Martínez, Javier, et al.
Publicado: (2021)

Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer
por: Hidalgo-Estévez, Alicia M., et al.
Publicado: (2020)

Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E(2) synthase up-regulation for colorectal cancer progression
por: Stamatakis, Konstantinos, et al.
Publicado: (2015)

DUSP5 and DUSP6 modulate corneal epithelial cell proliferation
por: Wang, Zheng, et al.
Publicado: (2010)

TCFL5 deficiency impairs the pachytene to diplotene transition during spermatogenesis in the mouse
por: Galán-Martínez, Javier, et al.
Publicado: (2022)

DUSP10 upregulation is a poor prognosticator and promotes cell proliferation and migration in glioma
por: Zhou, Fang, et al.
Publicado: (2023)

DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis
por: Tögel, Lars, et al.
Publicado: (2018)

Targeting of the Cancer-Associated Fibroblast—T-Cell Axis in Solid Malignancies
por: Harryvan, Tom J., et al.
Publicado: (2019)

DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

DUSP4 directly deubiquitinates and stabilizes Smad4 protein, promoting proliferation and metastasis of colorectal cancer cells
por: Xu, Weifeng, et al.
Publicado: (2020)

Extracellular BMP Antagonists, Multifaceted Orchestrators in the Tumor and Its Microenvironment
por: Ouahoud, Sarah, et al.
Publicado: (2020)

Author Correction: DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis
por: Tögel, Lars, et al.
Publicado: (2023)

DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer
por: Shen, Jiliang, et al.
Publicado: (2017)

DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling
por: Manley, Grace C. A., et al.
Publicado: (2019)

SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer
por: Shen, Hengyang, et al.
Publicado: (2021)

DUSPs, to MAP kinases and beyond
por: Huang, Ching-Yu, et al.
Publicado: (2012)

The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells
por: Thompson, Elliott M., et al.
Publicado: (2022)

Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis
por: Roelands, Jessica, et al.
Publicado: (2023)

Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression
por: Ding, Jie, et al.
Publicado: (2017)

Prostaglandin F(2α)-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity
por: Jiménez-Segovia, Alba, et al.
Publicado: (2019)

Corrigendum to “Prostaglandin F(2α)-induced prostate transmembrane protein, androgen induced 1 mediates ovarian cancer progression increasing epithelial plasticity” [Neoplasia 21 (2019) 1073–1084]
por: Jiménez-Segovia, Alba, et al.
Publicado: (2020)

Tripartite motif containing 24 regulates cell proliferation in colorectal cancer through YAP signaling
por: Xie, Wenlin, et al.
Publicado: (2020)

Serotonin acts through YAP to promote cell proliferation: mechanism and implication in colorectal cancer progression
por: Yu, Huangfei, et al.
Publicado: (2023)

Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer
por: Martínez-Martínez, Desirée, et al.
Publicado: (2021)

Downregulation of DUSP9 Promotes Tumor Progression and Contributes to Poor Prognosis in Human Colorectal Cancer
por: Qiu, Zhaoyan, et al.
Publicado: (2020)

The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib
por: Cheng, Guohua, et al.
Publicado: (2021)

DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
por: Ferguson, Bradley S., et al.
Publicado: (2021)

YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
por: Jiang, Linhua, et al.
Publicado: (2021)

Dual Specificity Phosphatase 6 (DUSP6) regulates CD4+ T cell functions and restrains the spontaneous colitis in IL-10 deficient mice
por: Bertin, Samuel, et al.
Publicado: (2014)

DUSP4 phosphatase puts the brakes on DLBCL
por: Rickert, Robert
Publicado: (2015)

Proapoptotic function of deubiquitinase DUSP31 in Drosophila
por: Sinenko, Sergey A.
Publicado: (2017)

Investigating the Role of DUSP4 in Uveal Melanoma
por: Aughton, Karen, et al.
Publicado: (2022)

BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation
por: Yang, Ziqing, et al.
Publicado: (2022)

Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5
por: Liu, Bin, et al.
Publicado: (2017)

DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway
por: Luo, Jing, et al.
Publicado: (2020)

Exosomal transfer of miR-769-5p promotes osteosarcoma proliferation and metastasis by targeting DUSP16
por: Liu, Wanshun, et al.
Publicado: (2021)

Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells
por: Wang, Lijuan, et al.
Publicado: (2013)

N6-Methyladenosine Modification of PTTG3P Contributes to Colorectal Cancer Proliferation via YAP1
por: Zheng, Yang, et al.
Publicado: (2021)

Tumor Promoting Function of DUSP10 in Non-Small Cell Lung Cancer Is Associated With Tumor-Promoting Cytokines
por: Wei, Xing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k3t99kqrdpn0gkienkncd4qcv4