Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones

Treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the development of drug resistance. The Warburg effect describes the ability of cancer cells to consume larger amounts of glucose compared to normal tissues. We identified derivatives of natural 1,4-naphthoquinones t...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Pelageev, Dmitry N., Hauschild, Jessica, Borisova, Ksenia L., Kaune, Moritz, Krisp, Christoph, Venz, Simone, Sabutskii, Yurii E., Khmelevskaya, Ekaterina A., Busenbender, Tobias, Denisenko, Vladimir A., Pokhilo, Natalia D., Atopkina, Lyubov N., Graefen, Markus, Schlüter, Hartmut, Stonik, Valentin A., Bokemeyer, Carsten, Anufriev, Victor Ph., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896172/
https://www.ncbi.nlm.nih.gov/pubmed/31671612
http://dx.doi.org/10.3390/cancers11111690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896172/
https://www.ncbi.nlm.nih.gov/pubmed/31671612
http://dx.doi.org/10.3390/cancers11111690

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