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Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
Treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the development of drug resistance. The Warburg effect describes the ability of cancer cells to consume larger amounts of glucose compared to normal tissues. We identified derivatives of natural 1,4-naphthoquinones t...
Autores principales: | Dyshlovoy, Sergey A., Pelageev, Dmitry N., Hauschild, Jessica, Borisova, Ksenia L., Kaune, Moritz, Krisp, Christoph, Venz, Simone, Sabutskii, Yurii E., Khmelevskaya, Ekaterina A., Busenbender, Tobias, Denisenko, Vladimir A., Pokhilo, Natalia D., Atopkina, Lyubov N., Graefen, Markus, Schlüter, Hartmut, Stonik, Valentin A., Bokemeyer, Carsten, Anufriev, Victor Ph., von Amsberg, Gunhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896172/ https://www.ncbi.nlm.nih.gov/pubmed/31671612 http://dx.doi.org/10.3390/cancers11111690 |
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