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Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats

Chronic pain is a persistent and debilitating health problem. Although the use of analgesics such as opioids is useful in mitigating pain, their prolonged use is associated with unwanted effects including abuse liability. This study assesses the antinociceptive effect of combining subtherapeutic dos...

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Detalles Bibliográficos
Autores principales: Alsalem, Mohammad, Altarifi, Ahmad, Haddad, Mansour, Aldossary, Sara A., Kalbouneh, Heba, Aldaoud, Nour, Saleh, Tareq, El-Salem, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896179/
https://www.ncbi.nlm.nih.gov/pubmed/31744226
http://dx.doi.org/10.3390/brainsci9110328