Cargando…

Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats

Chronic pain is a persistent and debilitating health problem. Although the use of analgesics such as opioids is useful in mitigating pain, their prolonged use is associated with unwanted effects including abuse liability. This study assesses the antinociceptive effect of combining subtherapeutic dos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alsalem, Mohammad, Altarifi, Ahmad, Haddad, Mansour, Aldossary, Sara A., Kalbouneh, Heba, Aldaoud, Nour, Saleh, Tareq, El-Salem, Khalid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896179/ https://www.ncbi.nlm.nih.gov/pubmed/31744226 http://dx.doi.org/10.3390/brainsci9110328

Ejemplares similares

Analgesic Effects and Impairment in Locomotor Activity Induced by Cannabinoid/Opioid Combinations in Rat Models of Chronic Pain
por: Alsalem, Mohammad, et al.
Publicado: (2020)

Effects of Dual Peroxisome Proliferator-Activated Receptors α and γ Activation in Two Rat Models of Neuropathic Pain
por: Alsalem, Mohammad, et al.
Publicado: (2019)

PM287. Mixtures of opioid receptor agonists and cannabinoid receptor agonists: enhanced antinociception without abuse liability
por: France, Charles P, et al.
Publicado: (2016)

Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat
por: Alsalem, Mohammad, et al.
Publicado: (2016)

Alcohol, Cannabinoids, and Opioids Abuse and Dependence Among Psychiatric Inpatients
por: Habibisaravi, Reza, et al.
Publicado: (2015)

A spider derived peptide, PnPP-19, induces central antinociception mediated by opioid and cannabinoid systems
por: da Fonseca Pacheco, Daniela, et al.
Publicado: (2016)

Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966
por: Reichenbach, Zachary W., et al.
Publicado: (2022)

Management of Sickle Cell Disease Pain among Adolescent and Pediatric Patients
por: Abdo, Samar, et al.
Publicado: (2019)

Role of opioid system in verapamil-induced antinociception in a rat model of orofacial pain
por: Tamaddonfard, Esmaeal, et al.
Publicado: (2014)

NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System
por: Vanegas, Horacio, et al.
Publicado: (2010)

Age of the donor affects the nature of in vitro cultured human dental pulp stem cells
por: Alzer, Heba, et al.
Publicado: (2021)

TRPV1: A Common Denominator Mediating Antinociceptive and Antiemetic Effects of Cannabinoids
por: Louis-Gray, Kathleen, et al.
Publicado: (2022)

Alkaptonuria with extensive ochronotic degeneration of the Achilles tendon and its surgical treatment: a case report and literature review
por: Mwafi, Nesrin, et al.
Publicado: (2021)

The role of cannabinoid CB1 receptors in the antinociceptive and reparative actions of mesenchymal stem cells in rats with peripheral neuropathic pain
por: Yerofeyeva, Anna‐Maria V., et al.
Publicado: (2023)

Evaluation of the antinociceptive effect of valerian and hops combination in experimental animal models: Involvement of the opioid system
por: Gammoh, Omar Salem, et al.
Publicado: (2023)

Synthesis, purification, characterization, and antinociceptive activity of opioids peptides
por: Nóbrega, Mariana, et al.
Publicado: (2014)

Peripheral Antinociception Induced by Aripiprazole Is Mediated by the Opioid System
por: Ferreira, Renata Cristina Mendes, et al.
Publicado: (2017)

Mirogabalin Decreases Pain-like Behaviours and Improves Opioid and Ketamine Antinociception in a Mouse Model of Neuropathic Pain
por: Zajączkowska, Renata, et al.
Publicado: (2022)

Antinociceptive effects of dehydrocorydaline in mouse models of inflammatory pain involve the opioid receptor and inflammatory cytokines
por: Yin, Zhi-Yu, et al.
Publicado: (2016)

The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors
por: Xu, Ying, et al.
Publicado: (2016)

Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism
por: Zhao, Guanghai, et al.
Publicado: (2021)

Estimation of sex based on metrics of the sternum in a contemporary Jordanian population: A computed tomographic study
por: Kalbouneh, Heba, et al.
Publicado: (2021)

Social Media Text Mining Framework for Drug Abuse: Development and Validation Study With an Opioid Crisis Case Analysis
por: Nasralah, Tareq, et al.
Publicado: (2020)

Reflections on the role of opioids in the treatment of chronic pain: a shared solution for prescription opioid abuse and pain
por: Thomas, D., et al.
Publicado: (2015)

δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats
por: Emerich, Bruna Luiza, et al.
Publicado: (2016)

Accessory Ossicles in the Region of the Foot and Ankle: An Epidemiologic Survey in a Jordanian Population
por: Kalbouneh, Heba, et al.
Publicado: (2021)

Antinociceptive effects of maprotiline in a rat model of peripheral neuropathic pain: possible involvement of opioid system
por: Banafshe, Hamid Reza, et al.
Publicado: (2015)

Hop Extract Produces Antinociception by Acting on Opioid System in Mice
por: Park, Soo-Hyun, et al.
Publicado: (2012)

Involvement of Cholinergic and Opioid System in γ-Terpinene-Mediated Antinociception
por: Passos, Flávia Franceli de Brito, et al.
Publicado: (2015)

Consensus‐based recommendations for titrating cannabinoids and tapering opioids for chronic pain control
por: Sihota, Aaron, et al.
Publicado: (2020)

Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV(1), Glutamate, and Opioid Receptors
por: Ping, Chung Pui, et al.
Publicado: (2018)

Assessment and Treatment of Abuse Risk in Opioid Prescribing for Chronic Pain
por: Jamison, Robert N., et al.
Publicado: (2011)

Predicting and Managing Pediatric Postoperative Pain in the Age of Opioid Abuse
por: Bernstein, Jaime L., et al.
Publicado: (2019)

(-)-Pentazocine induces visceral chemical antinociception, but not thermal, mechanical, or somatic chemical antinociception, in μ-opioid receptor knockout mice
por: Ide, Soichiro, et al.
Publicado: (2011)

Anti-inflammatory and antinociceptive effects of the selective cannabinoid CB(2) receptor agonist ABK5
por: Tang, Yaliang, et al.
Publicado: (2020)

Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats
por: Oehler, Beatrice, et al.
Publicado: (2017)

Dental pulp stem cells-derived schwann cells for peripheral nerve injury regeneration
por: Al-Zer, Heba, et al.
Publicado: (2015)

Emerging drugs of abuse: current perspectives on synthetic cannabinoids
por: Debruyne, Danièle, et al.
Publicado: (2015)

Acute Liver Injury Induced by Synthetic Cannabinoid Abuse
por: Shahbaz, Amir, et al.
Publicado: (2018)

The Endogenous Opioids Related with Antinociceptive Effects Induced by Electrical Stimulation into the Amygdala
por: Nakamura, Takami, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fvflp7krqmqs66771ba4vtaq7g