Detection of Enriched T Cell Epitope Specificity in Full T Cell Receptor Sequence Repertoires

High-throughput T cell receptor (TCR) sequencing allows the characterization of an individual's TCR repertoire and directly queries their immune state. However, it remains a non-trivial task to couple these sequenced TCRs to their antigenic targets. In this paper, we present a novel strategy to...

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Detalles Bibliográficos
Autores principales: Gielis, Sofie, Moris, Pieter, Bittremieux, Wout, De Neuter, Nicolas, Ogunjimi, Benson, Laukens, Kris, Meysman, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896208/
https://www.ncbi.nlm.nih.gov/pubmed/31849987
http://dx.doi.org/10.3389/fimmu.2019.02820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896208/
https://www.ncbi.nlm.nih.gov/pubmed/31849987
http://dx.doi.org/10.3389/fimmu.2019.02820

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