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Detection of Enriched T Cell Epitope Specificity in Full T Cell Receptor Sequence Repertoires

High-throughput T cell receptor (TCR) sequencing allows the characterization of an individual's TCR repertoire and directly queries their immune state. However, it remains a non-trivial task to couple these sequenced TCRs to their antigenic targets. In this paper, we present a novel strategy to...

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Detalles Bibliográficos
Autores principales:	Gielis, Sofie, Moris, Pieter, Bittremieux, Wout, De Neuter, Nicolas, Ogunjimi, Benson, Laukens, Kris, Meysman, Pieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896208/ https://www.ncbi.nlm.nih.gov/pubmed/31849987 http://dx.doi.org/10.3389/fimmu.2019.02820

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