Cell Surface GRP78 as a Death Receptor and an Anticancer Drug Target

Cell surface GRP78 (csGRP78, glucose-regulated protein 78 kDa) is preferentially overexpressed in aggressive, metastatic, and chemo-resistant cancers. GRP78 is best studied as a chaperone protein in the lumen of endoplasmic reticulum (ER), facilitating folding and secretion of the newly synthesized...

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Detalles Bibliográficos
Autores principales: Ge, Ruowen, Kao, Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896222/
https://www.ncbi.nlm.nih.gov/pubmed/31766302
http://dx.doi.org/10.3390/cancers11111787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896222/
https://www.ncbi.nlm.nih.gov/pubmed/31766302
http://dx.doi.org/10.3390/cancers11111787

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