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Severe Acute Malnutrition Results in Lower Lumefantrine Exposure in Children Treated With Artemether‐Lumefantrine for Uncomplicated Malaria

Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs. This population pharmacokinetic (PK)‐pharmacodynamic study included 131 SAM and 266 non‐SAM children administered...

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Detalles Bibliográficos
Autores principales: Chotsiri, Palang, Denoeud‐Ndam, Lise, Baudin, Elisabeth, Guindo, Ousmane, Diawara, Halimatou, Attaher, Oumar, Smit, Michiel, Guerin, Philippe J., Doumbo, Ogobara K., Wiesner, Lubbe, Barnes, Karen I., Hoglund, Richard M., Dicko, Alassane, Etard, Jean‐Francois, Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896236/
https://www.ncbi.nlm.nih.gov/pubmed/31152555
http://dx.doi.org/10.1002/cpt.1531