Mitochondrial tRNA(Ala) 5601C>T variant may affect the clinical expression of the LHON-related ND4 11778G>A mutation in a family

Certain mutations in mitochondrial DNA (mtDNA) are associated with Leber's hereditary optic neuropathy (LHON). In particular, the well-known NADH dehydrogenase 4 (ND4) m.11778G>A mutation is one of the most common LHON-associated primary mutations worldwide. However, how specific mtDNA mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Yu, Ye, Yu-Feng, Li, Mei-Ya, Xia, Bo-Hou, Leng, Jian-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896293/
https://www.ncbi.nlm.nih.gov/pubmed/31939618
http://dx.doi.org/10.3892/mmr.2019.10844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896293/
https://www.ncbi.nlm.nih.gov/pubmed/31939618
http://dx.doi.org/10.3892/mmr.2019.10844

Ejemplares similares