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Antifibrotic effects of specific siRNA targeting connective tissue growth factor delivered by polyethyleneimine-functionalized magnetic iron oxide nanoparticles on LX-2 cells

Connective tissue growth factor (CTGF) is a possible key determinant of progressive fibrosis. Nanotechnology has been considered as a potential tool for developing novel drug delivery systems for various diseases, including liver fibrosis. The present study aimed to investigate the potential antifib...

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Detalles Bibliográficos
Autores principales: Yu, Qin, Xiong, Xiaoqin, Zhao, Lei, Xu, Tingting, Wang, Qianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896301/
https://www.ncbi.nlm.nih.gov/pubmed/31746398
http://dx.doi.org/10.3892/mmr.2019.10834