Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke

BACKGROUND: Ischemic stroke is a leading cause of disability worldwide and characteristically accompanied by downregulation of the Wnt/β-catenin signaling. Activation of Wnt/β-catenin signaling emerges to attenuate neuroinflammation after ischemic stroke; however, its effect on modulating microglial...

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Detalles Bibliográficos
Autores principales: Song, Degang, Zhang, Xiangjian, Chen, Junmin, Liu, Xiaoxia, Xue, Jing, Zhang, Lan, Lan, Xifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896312/
https://www.ncbi.nlm.nih.gov/pubmed/31810470
http://dx.doi.org/10.1186/s12974-019-1660-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896312/
https://www.ncbi.nlm.nih.gov/pubmed/31810470
http://dx.doi.org/10.1186/s12974-019-1660-8

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