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Increased mitochondrial DNA copy number protects hair cells and HEI-OC1 cells against drug-induced apoptosis
Several factors trigger apoptosis in cochlear hair cells. Previous studies have shown that mitochondria play key roles in apoptosis, but the role of mitochondrial deoxyribonucleic acid (mtDNA) copy number in the pathogenesis of hair cell apoptosis remains largely unknown. We used mouse cochlear hair...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896317/ https://www.ncbi.nlm.nih.gov/pubmed/31939628 http://dx.doi.org/10.3892/mmr.2019.10838 |