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Increased mitochondrial DNA copy number protects hair cells and HEI-OC1 cells against drug-induced apoptosis

Several factors trigger apoptosis in cochlear hair cells. Previous studies have shown that mitochondria play key roles in apoptosis, but the role of mitochondrial deoxyribonucleic acid (mtDNA) copy number in the pathogenesis of hair cell apoptosis remains largely unknown. We used mouse cochlear hair...

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Detalles Bibliográficos
Autores principales:	Mei, Honglin, Mei, Dongmei, Yu, Huiqian, Sun, Shan, Chen, Yan, Zhang, Yanping, Chai, Renjie, Li, Huawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896317/ https://www.ncbi.nlm.nih.gov/pubmed/31939628 http://dx.doi.org/10.3892/mmr.2019.10838

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