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Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma

BACKGROUND: Identification of novel cancer-associated splice variants is of potential diagnostic, prognostic and therapeutic importance. NF-Y transcription factor is comprised of NF-YA, NF-YB and NF-YC subunits, binds inverted CCAAT-boxes in ≈70% of gene promoters, regulates > 1000 cancer-associa...

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Detalles Bibliográficos
Autores principales: Cappabianca, Lucia, Farina, Antonietta Rosella, Di Marcotullio, Lucia, Infante, Paola, De Simone, Daniele, Sebastiano, Michela, Mackay, Andrew Reay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896337/
https://www.ncbi.nlm.nih.gov/pubmed/31805994
http://dx.doi.org/10.1186/s13046-019-1481-8