Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry

The differential scanning fluorimetry (DSF) screening of 5.692 fragments in combination with benzenesulfonamide (BSA) against bovine carbonic anhydrase (bCA) delivered >100 hits that either caused, on their own, a significant thermal shift (ΔT(m), °C) in the protein melting temperature or signifi...

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Detalles Bibliográficos
Autores principales: Krasavin, Mikhail, Kalinin, Stanislav, Zozulya, Sergey, Gryniukova, Anastasiia, Borysko, Petro, Angeli, Andrea, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896451/
https://www.ncbi.nlm.nih.gov/pubmed/31797704
http://dx.doi.org/10.1080/14756366.2019.1698562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896451/
https://www.ncbi.nlm.nih.gov/pubmed/31797704
http://dx.doi.org/10.1080/14756366.2019.1698562

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