Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment

BACKGROUND: Extracellular vesicles (EVs) are nano-sized particles present in most body fluids including cerebrospinal fluid (CSF). Little is known about CSF EV proteins in HIV+ individuals. Here, we characterize the CSF EV proteome in HIV+ subjects and its relationship to neuroinflammation, stress r...

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Detalles Bibliográficos
Autores principales: Guha, Debjani, Lorenz, David R., Misra, Vikas, Chettimada, Sukrutha, Morgello, Susan, Gabuzda, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896665/
https://www.ncbi.nlm.nih.gov/pubmed/31805958
http://dx.doi.org/10.1186/s12974-019-1617-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896665/
https://www.ncbi.nlm.nih.gov/pubmed/31805958
http://dx.doi.org/10.1186/s12974-019-1617-y

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