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Remodeling of hepatic stellate cells orchestrated the stroma-derived oxaliplatin-resistance through CCN3 paracrine in hepatocellular carcinoma

BACKGROUND: Hepatic stellate cells (HSCs) have a key role in fibrogenesis and in the filtrates of the hepatocellular carcinoma (HCC) stroma, in which they are remodeled and play a critical role in HCC progression. However, the precise role of HSCs trending, infiltration and paracrine in orchestratin...

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Detalles Bibliográficos
Autores principales: Liao, Xia, Bu, Yang, Chang, Fan, Jia, Fengan, Song, Ge, Xiao, Xuelian, Zhang, Mei, Ning, Pengbo, Jia, Qingan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896671/
https://www.ncbi.nlm.nih.gov/pubmed/31805888
http://dx.doi.org/10.1186/s12885-019-6362-1