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The impact of RNA extraction method on accurate RNA sequencing from formalin-fixed paraffin-embedded tissues

BACKGROUND: Utilization of RNA sequencing methods to measure gene expression from archival formalin-fixed paraffin-embedded (FFPE) tumor samples in translational research and clinical trials requires reliable interpretation of the impact of pre-analytical variables on the data obtained, particularly...

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Detalles Bibliográficos
Autores principales: Marczyk, Michal, Fu, Chunxiao, Lau, Rosanna, Du, Lili, Trevarton, Alexander J., Sinn, Bruno V., Gould, Rebekah E., Pusztai, Lajos, Hatzis, Christos, Symmans, W. Fraser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896723/
https://www.ncbi.nlm.nih.gov/pubmed/31805884
http://dx.doi.org/10.1186/s12885-019-6363-0