Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells

BACKGROUND: The tumor suppressor actions of hexamethylene bis-acetamide (HMBA)-inducible protein 1 (HEXIM1) in the breast, prostate, melanomas, and AML have been reported by our group and others. Increased HEXIM1 expression caused differentiation and inhibited proliferation and metastasis of cancer...

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Detalles Bibliográficos
Autores principales: Montano, Monica M., Yeh, I-Ju, Chen, Yinghua, Hernandez, Chris, Kiselar, Janna G., de la Fuente, Maria, Lawes, Adriane M., Nieman, Marvin T., Kiser, Philip D., Jacobberger, James, Exner, Agata A., Lawes, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896798/
https://www.ncbi.nlm.nih.gov/pubmed/31805991
http://dx.doi.org/10.1186/s13058-019-1228-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896798/
https://www.ncbi.nlm.nih.gov/pubmed/31805991
http://dx.doi.org/10.1186/s13058-019-1228-7

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