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Clustering-independent analysis of genomic data using spectral simplicial theory

The prevailing paradigm for the analysis of biological data involves comparing groups of replicates from different conditions (e.g. control and treatment) to statistically infer features that discriminate them (e.g. differentially expressed genes). However, many situations in modern genomics such as...

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Detalles Bibliográficos
Autores principales: Govek, Kiya W., Yamajala, Venkata S., Camara, Pablo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897424/
https://www.ncbi.nlm.nih.gov/pubmed/31756191
http://dx.doi.org/10.1371/journal.pcbi.1007509