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Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

The thymic function to produce self-protective and self-tolerant T cells is chiefly mediated by cortical thymic epithelial cells (cTECs) and medullary TECs (mTECs). Recent studies including single-cell transcriptomic analyses have highlighted a rich diversity in functional mTEC subpopulations. Becau...

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Detalles Bibliográficos
Autores principales: Ohigashi, Izumi, Tanaka, Yu, Kondo, Kenta, Fujimori, Sayumi, Kondo, Hiroyuki, Palin, Amy C., Hoffmann, Victoria, Kozai, Mina, Matsushita, Yosuke, Uda, Shinsuke, Motosugi, Ryo, Hamazaki, Jun, Kubota, Hiroyuki, Murata, Shigeo, Tanaka, Keiji, Katagiri, Toyomasa, Kosako, Hidetaka, Takahama, Yousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897492/
https://www.ncbi.nlm.nih.gov/pubmed/31775054
http://dx.doi.org/10.1016/j.celrep.2019.10.079