Chlorpromazine protects against acetaminophen-induced liver injury in mice by modulating autophagy and c-Jun N-terminal kinase activation

BACKGROUND AND AIM: Overdose of acetaminophen (APAP) leads to liver injury, which is one of the most common causes of liver failure in the United States. We previously demonstrated that pharmacological activation of autophagy protects against APAP-induced liver injury in mice via removal of damaged...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Ni, Hong-Min, Jaeschke, Hartmut, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897503/
https://www.ncbi.nlm.nih.gov/pubmed/31815033
http://dx.doi.org/10.1016/j.livres.2019.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897503/
https://www.ncbi.nlm.nih.gov/pubmed/31815033
http://dx.doi.org/10.1016/j.livres.2019.01.004

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