Cargando…

Expedient synthesis of E-hydrazone esters and 1H-indazole scaffolds through heterogeneous single-atom platinum catalysis

Unprotected E-hydrazone esters are prized building blocks for the preparation of 1H-indazoles and countless other N-containing biologically active molecules. Despite previous advances, efficient and stereoselective synthesis of these compounds remains nontrivial. Here, we show that Pt single atoms a...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Cuibo, Chen, Zhongxin, Yan, Huan, Xi, Shibo, Yam, Kah Meng, Gao, Jiajian, Du, Yonghua, Li, Jing, Zhao, Xiaoxu, Xie, Keyu, Xu, Haisen, Li, Xing, Leng, Kai, Pennycook, Stephen J., Liu, Bin, Zhang, Chun, Koh, Ming Joo, Loh, Kian Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897547/
https://www.ncbi.nlm.nih.gov/pubmed/31840074
http://dx.doi.org/10.1126/sciadv.aay1537