Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling

Healthy aging results in cardiac structural and electrical remodeling that increases susceptibility to cardiovascular diseases. Relaxin, an insulin-like hormone, suppresses atrial fibrillation, inflammation and fibrosis in aged rats but the mechanisms-of-action are unknown. Here we show that relaxin...

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Detalles Bibliográficos
Autores principales: Martin, Brian, Gabris, Beth, Barakat, Amr F., Henry, Brian L., Giannini, Marianna, Reddy, Rajiv P., Wang, Xuewen, Romero, Guillermo, Salama, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897890/
https://www.ncbi.nlm.nih.gov/pubmed/31811156
http://dx.doi.org/10.1038/s41598-019-53867-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897890/
https://www.ncbi.nlm.nih.gov/pubmed/31811156
http://dx.doi.org/10.1038/s41598-019-53867-y

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