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In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics

The long-term expansion of keratinocytes under conditions that avoid xenogeneic components (i.e. animal serum- and feeder cell-free) generally causes diminished proliferation and increased terminal differentiation. Here we present a culture system free of xenogeneic components that retains the self-...

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Detalles Bibliográficos
Autores principales: Wong, Chee-Wai, LeGrand, Catherine F., Kinnear, Beverley F., Sobota, Radoslaw M., Ramalingam, Rajkumar, Dye, Danielle E., Raghunath, Michael, Lane, E. Birgitte, Coombe, Deirdre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897920/
https://www.ncbi.nlm.nih.gov/pubmed/31811191
http://dx.doi.org/10.1038/s41598-019-54793-9