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Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer
Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To identify gene signatures regulated by epigenetic mechanisms in OC cells carrying BRCA1 mutations, we assessed cellular responses to epigenome modifiers an...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897992/ https://www.ncbi.nlm.nih.gov/pubmed/31840082 http://dx.doi.org/10.1038/s41698-019-0103-4 |