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Murine xenograft bioreactors for human immunopeptidome discovery

The study of peptides presented by MHC class I and class II molecules is limited by the need for relatively large cell numbers, especially when studying post-translationally modified or otherwise rare peptide species. To overcome this problem, we pose the hypothesis that human cells grown as xenogra...

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Detalles Bibliográficos
Autores principales: Heather, James M., Myers, Paisley T., Shi, Feng, Aziz-Zanjani, Mohammad Ovais, Mahoney, Keira E., Perez, Matthew, Morin, Benjamin, Brittsan, Christine, Shabanowitz, Jeffrey, Hunt, Donald F., Cobbold, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898210/
https://www.ncbi.nlm.nih.gov/pubmed/31811195
http://dx.doi.org/10.1038/s41598-019-54700-2