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Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
Mucosal healing plays a critical role in combatting the effects of inflammatory bowel disease, fistulae and ulcers. While most treatments for such diseases focus on systemically delivered anti-inflammatory drugs, often leading to detrimental side effects, mucosal healing agents that target the gut e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898321/ https://www.ncbi.nlm.nih.gov/pubmed/31811125 http://dx.doi.org/10.1038/s41467-019-13336-6 |