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Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

Mucosal healing plays a critical role in combatting the effects of inflammatory bowel disease, fistulae and ulcers. While most treatments for such diseases focus on systemically delivered anti-inflammatory drugs, often leading to detrimental side effects, mucosal healing agents that target the gut e...

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Detalles Bibliográficos
Autores principales: Praveschotinunt, Pichet, Duraj-Thatte, Anna M., Gelfat, Ilia, Bahl, Franziska, Chou, David B., Joshi, Neel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898321/
https://www.ncbi.nlm.nih.gov/pubmed/31811125
http://dx.doi.org/10.1038/s41467-019-13336-6