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In silico prediction of high-resolution Hi-C interaction matrices

The three-dimensional (3D) organization of the genome plays an important role in gene regulation bringing distal sequence elements in 3D proximity to genes hundreds of kilobases away. Hi-C is a powerful genome-wide technique to study 3D genome organization. Owing to experimental costs, high resoluti...

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Detalles Bibliográficos
Autores principales: Zhang, Shilu, Chasman, Deborah, Knaack, Sara, Roy, Sushmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898380/
https://www.ncbi.nlm.nih.gov/pubmed/31811132
http://dx.doi.org/10.1038/s41467-019-13423-8