Cargando…

Podocyte hypertrophic stress and detachment precedes hyperglycemia or albuminuria in a rat model of obesity and type2 diabetes-associated nephropathy

Type2 diabetes-associated nephropathy is the commonest cause of renal failure. Mechanisms responsible are controversial. Leptin-deficient hyperphagic Zucker (fa/fa) rats were modeled to test the hypothesis that glomerular enlargement drives podocyte hypertrophic stress leading to accelerated podocyt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Minakawa, Akihiro, Fukuda, Akihiro, Sato, Yuji, Kikuchi, Masao, Kitamura, Kazuo, Wiggins, Roger C., Fujimoto, Shouichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898392/ https://www.ncbi.nlm.nih.gov/pubmed/31811176 http://dx.doi.org/10.1038/s41598-019-54692-z

Ejemplares similares

Urinary podocyte mRNAs precede microalbuminuria as a progression risk marker in human type 2 diabetic nephropathy
por: Fukuda, Akihiro, et al.
Publicado: (2020)

Dasatinib-induced nephrotic syndrome in a patient with chronic myelogenous leukemia: a case report
por: Ochiai, Shoko, et al.
Publicado: (2019)

Concurrent minimal change nephrotic syndrome and type 1 diabetes mellitus in an adult Japanese woman: a case report
por: Nishizono, Ryuzoh, et al.
Publicado: (2020)

Triptolide markedly attenuates albuminuria and podocyte injury in an animal model of diabetic nephropathy
por: MA, RUIXIA, et al.
Publicado: (2013)

Podocyte Foot Process Effacement Precedes Albuminuria and Glomerular Hypertrophy in CD2-Associated Protein Deficient Mice
por: Basgen, John M., et al.
Publicado: (2021)

Glomerular Endothelial Cell Injury and Damage Precedes That of Podocytes in Adriamycin-Induced Nephropathy
por: Sun, Yu Bo Yang, et al.
Publicado: (2013)

Tiaolipiwei Acupuncture Reduces Albuminuria by Alleviating Podocyte Lesions in a Rat Model of Diabetic Nephropathy
por: Zhang, Zhilong, et al.
Publicado: (2018)

Gold nanoparticles attenuate albuminuria by inhibiting podocyte injury in a rat model of diabetic nephropathy
por: Alomari, Ghada, et al.
Publicado: (2019)

Structural Analysis of How Podocytes Detach from the Glomerular Basement Membrane Under Hypertrophic Stress
por: Kriz, Wilhelm, et al.
Publicado: (2014)

Morphine Induces Albuminuria by Compromising Podocyte Integrity
por: Lan, Xiqian, et al.
Publicado: (2013)

Podocyte number and density changes during early human life
por: Kikuchi, Masao, et al.
Publicado: (2016)

Decreased Podocyte Vesicle Transcytosis and Albuminuria in APC C-Terminal Deficiency Mice with Puromycin-Induced Nephrotic Syndrome
por: Hatakeyama, Saaya, et al.
Publicado: (2021)

Saxagliptin Attenuates Albuminuria by Inhibiting Podocyte Epithelial- to-Mesenchymal Transition via SDF-1α in Diabetic Nephropathy
por: Chang, Yun-peng, et al.
Publicado: (2017)

Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats
por: Asakawa, Shinichiro, et al.
Publicado: (2017)

YAP Translocation Precedes Cytoskeletal Rearrangement in Podocyte Stress Response: A Podometric Investigation of Diabetic Nephropathy
por: Haley, Kathryn E., et al.
Publicado: (2021)

A Book of Detachable Diet Lists, for Albuminuria
Publicado: (1895)

Controversies in Podocyte Loss: Death or Detachment?
por: Yin, Lijun, et al.
Publicado: (2021)

Characterisation of N-terminal pro-brain natriuretic peptide in dialysis patients and its reduced prognostic significance in the elderly
por: Sato, Yuji, et al.
Publicado: (2019)

Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy
por: Weil, E Jennifer, et al.
Publicado: (2012)

Hyperglycemia and Renal Mass Ablation Synergistically Augment Albuminuria in the Diabetic Subtotally Nephrectomized Rat: Implications for Modeling Diabetic Nephropathy
por: Chen, Li-Hao, et al.
Publicado: (2012)

Editorial: Podocyte Pathology and Nephropathy
por: Lewko, Barbara, et al.
Publicado: (2015)

A Book of Detachable Diet Lists; for Albuminuria, Etc., Etc.
Publicado: (1895)

Endothelial-Podocyte Crosstalk: The Missing Link Between Endothelial Dysfunction and Albuminuria in Diabetes
por: Siddiqi, Ferhan S., et al.
Publicado: (2013)

Aristolochic Acid Causes Albuminuria by Promoting Mitochondrial DNA Damage and Dysfunction in Podocyte
por: Zhou, Yang, et al.
Publicado: (2013)

Elevation of Arginase-II in Podocytes Contributes to Age-Associated Albuminuria in Male Mice
por: Ajalbert, Guillaume, et al.
Publicado: (2023)

Editorial: Podocyte Pathology and Nephropathy—An Update
por: Lehtonen, Sanna, et al.
Publicado: (2019)

Epigenetic Alterations in Podocytes in Diabetic Nephropathy
por: Sugita, Erina, et al.
Publicado: (2021)

Podocyte puzzle: IgA nephropathy
por: Bharati, Joyita, et al.
Publicado: (2023)

Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis
por: Takiue, Keiichi, et al.
Publicado: (2012)

Mechanism Underlying Selective Albuminuria in Minimal Change Nephrotic Syndrome
por: Tojo, Akihiro
Publicado: (2019)

Podocytes … What’s Under Yours? (Podocytes and Foot Processes and How They Change in Nephropathy)
por: Neal, Chris R.
Publicado: (2015)

N-terminal-pro-B-type-natriuretic peptide associated with 2-year mortality from both cardiovascular and non-cardiovascular origins in prevalent chronic hemodialysis patients
por: Kawagoe, Chihiro, et al.
Publicado: (2018)

Rosmarinic acid monotherapy is better than the combination of rosmarinic acid and telmisartan in preventing podocyte detachment and inhibiting the progression of diabetic nephropathy in rats
por: Samsu, Nur, et al.
Publicado: (2019)

Case Report: A Case of Encephalopathy Presenting the Lentiform Fork Sign on MRI in a Diabetic Dialysis Patient
por: Ishizaki, Yuri, et al.
Publicado: (2021)

Relationship between Hemoglobin Levels Corrected by Interdialytic Weight Gain and Mortality in Japanese Hemodialysis Patients: Miyazaki Dialysis Cohort Study
por: Toida, Tatsunori, et al.
Publicado: (2017)

Podocyte Pathology and Nephropathy – Sphingolipids in Glomerular Diseases
por: Merscher, Sandra, et al.
Publicado: (2014)

Metadherin facilitates podocyte apoptosis in diabetic nephropathy
por: Liu, Wen-Ting, et al.
Publicado: (2016)

MicroRNAs in Podocyte Injury in Diabetic Nephropathy
por: Ishii, Hiroki, et al.
Publicado: (2020)

MicroRNAs for podocyte injury in diabetic nephropathy
por: Morishita, Yoshiyuki
Publicado: (2021)

Mechanisms of podocyte injury and implications for diabetic nephropathy
por: Barutta, Federica, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t8emfa7gn2igusvvgd8751a06l