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DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis
Altered aquaporin 5 (AQP5) expression in immune cells impacts on key mechanisms of inflammation and is associated with sepsis survival. Since epigenetic regulation via DNA methylation might contribute to a differential AQP5 expression in sepsis, we tested the hypotheses that DNA methylation of the A...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898603/ https://www.ncbi.nlm.nih.gov/pubmed/31811204 http://dx.doi.org/10.1038/s41598-019-55051-8 |