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Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts

Licensed influenza virus vaccines target the head domain of the hemagglutinin (HA) glycoprotein which undergoes constant antigenic drift. The highly conserved HA stalk domain is an attractive target to increase immunologic breadth required for universal influenza virus vaccines. We tested the hypoth...

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Detalles Bibliográficos
Autores principales: Nachbagauer, Raffael, Salaun, Bruno, Stadlbauer, Daniel, Behzadi, Mohammad A., Friel, Damien, Rajabhathor, Arvind, Choi, Angela, Albrecht, Randy A., Debois, Muriel, García-Sastre, Adolfo, Rouxel, Ronan N., Sun, Weina, Palese, Peter, Mallett, Corey P., Innis, Bruce L., Krammer, Florian, Claeys, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898674/
https://www.ncbi.nlm.nih.gov/pubmed/31839997
http://dx.doi.org/10.1038/s41541-019-0147-z