Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition

BACKGROUND: Unlike some adult cancers, most pediatric cancers are considered immunologically cold and generally less responsive to immunotherapy. While immunotherapy has already been incorporated into standard of care treatment for pediatric patients with high-risk neuroblastoma, overall survival re...

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Detalles Bibliográficos
Autores principales: Voeller, Julie, Erbe, Amy K., Slowinski, Jacob, Rasmussen, Kayla, Carlson, Peter M., Hoefges, Anna, VandenHeuvel, Sabrina, Stuckwisch, Ashley, Wang, Xing, Gillies, Stephen D., Patel, Ravi B., Farrel, Alvin, Rokita, Jo Lynne, Maris, John, Hank, Jacquelyn A., Morris, Zachary S., Rakhmilevich, Alexander L., Sondel, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898936/
https://www.ncbi.nlm.nih.gov/pubmed/31810498
http://dx.doi.org/10.1186/s40425-019-0823-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898936/
https://www.ncbi.nlm.nih.gov/pubmed/31810498
http://dx.doi.org/10.1186/s40425-019-0823-6

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