Comparative transcriptomics reveals PrrAB-mediated control of metabolic, respiration, energy-generating, and dormancy pathways in Mycobacterium smegmatis

BACKGROUND: Mycobacterium smegmatis is a saprophytic bacterium frequently used as a genetic surrogate to study pathogenic Mycobacterium tuberculosis. The PrrAB two-component genetic regulatory system is essential in M. tuberculosis and represents an attractive therapeutic target. In this study, tran...

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Detalles Bibliográficos
Autores principales: Maarsingh, Jason D., Yang, Shanshan, Park, Jin G., Haydel, Shelley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898941/
https://www.ncbi.nlm.nih.gov/pubmed/31810444
http://dx.doi.org/10.1186/s12864-019-6105-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898941/
https://www.ncbi.nlm.nih.gov/pubmed/31810444
http://dx.doi.org/10.1186/s12864-019-6105-3

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