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C. elegans Runx/CBFβ suppresses POP-1 TCF to convert asymmetric to proliferative division of stem cell-like seam cells

A correct balance between proliferative and asymmetric cell divisions underlies normal development, stem cell maintenance and tissue homeostasis. What determines whether cells undergo symmetric or asymmetric cell division is poorly understood. To gain insight into the mechanisms involved, we studied...

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Detalles Bibliográficos
Autores principales: van der Horst, Suzanne E. M., Cravo, Janine, Woollard, Alison, Teapal, Juliane, van den Heuvel, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899014/
https://www.ncbi.nlm.nih.gov/pubmed/31740621
http://dx.doi.org/10.1242/dev.180034