Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials

OBJECTIVE: Amantadine blocks N-methyl-D-aspartate (NMDA) receptors and has dopaminergic and noradrenergic action, a neurochemical profile that suggests its potential as an antidepressant drug. We conducted a systematic review of preclinical and clinical studies addressing the effects of amantadine i...

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Detalles Bibliográficos
Autores principales: Raupp-Barcaro, Inara F., Vital, Maria A., Galduróz, José C., Andreatini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Psiquiatria 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899375/
https://www.ncbi.nlm.nih.gov/pubmed/29898194
http://dx.doi.org/10.1590/1516-4446-2017-2393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899375/
https://www.ncbi.nlm.nih.gov/pubmed/29898194
http://dx.doi.org/10.1590/1516-4446-2017-2393

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