Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51

DNA double-strand breaks (DSBs) are deleterious and tumorigenic but could also be essential for DNA-based processes. Yet the landscape of physiological DSBs and their role and repair are still elusive. Here, we mapped DSBs at high resolution in cancer and non-tumorigenic cells and found a transcript...

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Detalles Bibliográficos
Autores principales: Hazan, Idit, Monin, Jonathan, Bouwman, Britta A.M., Crosetto, Nicola, Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899447/
https://www.ncbi.nlm.nih.gov/pubmed/31618627
http://dx.doi.org/10.1016/j.celrep.2019.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899447/
https://www.ncbi.nlm.nih.gov/pubmed/31618627
http://dx.doi.org/10.1016/j.celrep.2019.09.001

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