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Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51
DNA double-strand breaks (DSBs) are deleterious and tumorigenic but could also be essential for DNA-based processes. Yet the landscape of physiological DSBs and their role and repair are still elusive. Here, we mapped DSBs at high resolution in cancer and non-tumorigenic cells and found a transcript...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899447/ https://www.ncbi.nlm.nih.gov/pubmed/31618627 http://dx.doi.org/10.1016/j.celrep.2019.09.001 |