Disruption of the Key Ca(2+) Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking

Voltage-gated calcium channels are exquisitely Ca(2+) selective, conferred primarily by four conserved pore-loop glutamate residues contributing to the selectivity filter. There has been little previous work directly measuring whether the trafficking of calcium channels requires their ability to bin...

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Detalles Bibliográficos
Autores principales: Meyer, James O., Dahimene, Shehrazade, Page, Karen M., Ferron, Laurent, Kadurin, Ivan, Ellaway, Joseph I.J., Zhao, Pengxiang, Patel, Tarun, Rothwell, Simon W., Lin, Peipeng, Pratt, Wendy S., Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899504/
https://www.ncbi.nlm.nih.gov/pubmed/31577951
http://dx.doi.org/10.1016/j.celrep.2019.08.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899504/
https://www.ncbi.nlm.nih.gov/pubmed/31577951
http://dx.doi.org/10.1016/j.celrep.2019.08.079

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