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Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder

RNA sequencing analyses are often limited to identifying lowest p value transcripts, which does not address polygenic phenomena. To overcome this limitation, we developed an integrative approach that combines large-scale transcriptomic meta-analysis of patient brain tissues with single-cell sequenci...

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Detalles Bibliográficos
Autores principales: Lobentanzer, Sebastian, Hanin, Geula, Klein, Jochen, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899527/
https://www.ncbi.nlm.nih.gov/pubmed/31618642
http://dx.doi.org/10.1016/j.celrep.2019.09.017