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Nucleophilicity of Glutathione: A Link to Michael Acceptor Reactivities
Deprotonated glutathione is among the most potent biological nucleophiles and plays an important physiological role in cellular detoxification by forming covalent conjugates with Michael acceptors. The electrophilicity E of various Michael acceptors was characterized recently according to the Patz–M...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899611/ https://www.ncbi.nlm.nih.gov/pubmed/31560405 http://dx.doi.org/10.1002/anie.201909803 |